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Sample size guidelines for logistic regression from observational studies with large population: emphasis on the accuracy between statistics and parameters based on real life clinical data

Evidence is primarily drawn from tobacco industry data and lacks research on long-term HnB use effects on health [footnote 30]

To note, similar reductions in endothelial-dependent dilation have been identified after a single exposure to combustible tobacco products or e-cigarettes [115], although contradictory results are also available, supporting that acute exposure to neither combustible tobacco cigarettes nor ENDS had an effect on vascular function [87]